Alumni reunions have a history going back to the earliest years of the college. In 1862 former students returned to Alma Mater to catch up with one another. Presently, particular class reunions are scheduled every five years for the fifth to the twenty-fifth reunions during Homecoming Weekend in the fall. In the spring Commencement weekend Wheaton hosts alumni celebrating their thirtieth through seventy-fifth reunions.

Since 1860 more than 48,000 graduates have left campus to perform various roles in society, in the arts, government, business, education, ministry or the home, so that they may have an impact for Christ and His Kingdom.