On October 16th 1963 on the property of Judge Joseph Sam Perry of Glen Ellyn, the remains of an 11,000-year-old mastodon were found during digging for a man-made lake. Upon hearing this news Judge Perry called for help from Wheaton College, and Dr. Douglas Block of the geology department was soon put in charge of the excavation of the bones. More than 55% of the mastodon's bones were found, and the basement of Breyer Building was used as temporary storage space for the skeleton for the restoration process. It was Dr. Donald C. Boardman, then chair of the geology department, who was placed in charge of the restoration which took over 11 years to complete. During this time Dr. Boardman visited every Mastodon exhibit in North America and Europe so as to see how best to display Wheaton's skeleton. It was decided in the late 1960's that the mastodon's remains would be displayed in a special wing of the new science building that was being planned at that time; the wing was named the Edwin F. Deicke Exhibit Hall after one of the generous financial donors who made the Perry Mastodon project possible. Local Glen Ellyn artist, Richard Rush, designed the display that the skeleton now stands in. The Perry Mastodon Exhibit was officially dedicated on January 18, 1975. The Perry Mastodon is the second mastodon skeleton to be found in DuPage County, the first being found in 1869 by Ned Jayne.

One of the better student pranks in Wheaton's history involved the Perry Mastodon not long after its dedication on the 22nd of November 1975. A phony recording was found to have replaced the original exhibit narration. This prank, since called the Mastodon tape prank, was the work of Larry Shackley ('77) and Dave Watt who recorded the fake tape in the WETN studios. The tape told a reworked and fanciful history of Perry Mastodon that included being frozen in a giant ice cube for thousands of years, being tranquilized by Judge Perry after reawakening, having half of its body removed for use in the cafeteria, and knowing how to talk and dance among other things.